353487-64-6
353487-64-6
Chemical Structure
hMCH-1R antagonist 1
- CAS No.: 353487-64-6
- Formula:C49H82N16O11S3
- Molecular Weight:1167.47
InChIKey: GCICFXMYTKDVNK-ROOPJIIGSA-N
SMILES: O=C([C@@H](NC([C@@H](NC(CCCCNC([C@@H](NC([C@H](CSSC[C@H](NC(CCCCNC1=O)=O)C(N)=O)NC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)CCSC)=O)=O)CCCNC(N)=N)=O)C(C)C)N[C@H]1CC2=CC=C(C=C2)O
Biological Activity: hMCH-1R antagonist 1 (Compound 30) is an effective and selective antagonist of human melanin-concentrating hormone receptor 1 (hMCHR1) with an KB value of 3.6 nM. HMCH-1R antagonist 1 can bind to hMCHR1 and hMCHR2 with IC50 values of 65 nM and 49 nM, respectively. HMCH-1R antagonistist 1 can be used for metabolic research[1].
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hMCH-1R antagonist 1 | hMCH-1R antagonist 1 (Compound 30) is an effective and selective antagonist of human melanin-concentrating hormone receptor 1 (hMCHR1) with an KB value of 3.6 nM. HMCH-1R antagonist 1 can bind to hMCHR1 and hMCHR2 with IC50 values of 65 nM and 49 nM, respectively. HMCH-1R antagonistist 1 can be used for metabolic research. | |||||||||||||||||||||
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