355140-49-7
355140-49-7
Chemical Structure
Ac-Nle-Pro-Nle-Asp-AMC
- CAS. Nr.: 355140-49-7
- Formula:C33H45N5O9
- Molecular Weight:655.74
InChIKey: WPTAROWBMZVECB-CQJMVLFOSA-N
SMILES: CCCC[C@H](NC([C@@H]1CCCN1C([C@@H](NC(C)=O)CCCC)=O)=O)C(N[C@H](C(NC2=CC3=C(C(C)=CC(O3)=O)C=C2)=O)CC(O)=O)=O
Biological Activity: Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Ac-Nle-Pro-Nle-Asp-AMC | 99.36% | Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis. | ||||||||||||||||||||
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References
- [1]. Dunlop RA, et al. The impact of specific oxidized amino acids on protein turnover in J774 cells. Biochem J. 2008 Feb 15;410(1):131-40. [Content Brief]
- [2]. Kirk-Ballard H, et al. An extract of Artemisia dracunculus L. inhibits ubiquitin-proteasome activity and preserves skeletal muscle mass in a murine model of diabetes. PLoS One. 2013;8(2):e57112. [Content Brief]
- [3]. Pakavathkumar P, et al. Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine. Sci Rep. 2015 Sep 24;5:13730. [Content Brief]
