Ac-Nle-Pro-Nle-Asp-AMC
Based on 1 Customer Validation
Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis.
For research use only. We do not sell to patients.
- Purity: 99.36%
- CAS No.: 355140-49-7
- Formula: C33H45N5O9
- Molecular Weight:655.74
-
Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Metabolism/Protease Compound Library
HY-L012
-
Ubiquitination Compound Library
HY-L050
-
Peptide Library
HY-L105
-
Heterocyclic Compound Library
HY-L138
-
MCE Bioactive Compound Library
HY-L001V
-
Peptide Compound Library
HY-L105S
-
High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
-
CAS No. 355140-49-7
-
Appearance Solid
-
Molecular Weight 655.74
-
Formula C33H45N5O9
-
Color White to off-white
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (152.50 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Dunlop RA, et al. The impact of specific oxidized amino acids on protein turnover in J774 cells. Biochem J. 2008 Feb 15;410(1):131-40. [Content Brief]
[2]. Kirk-Ballard H, et al. An extract of Artemisia dracunculus L. inhibits ubiquitin-proteasome activity and preserves skeletal muscle mass in a murine model of diabetes. PLoS One. 2013;8(2):e57112. [Content Brief]
[3]. Pakavathkumar P, et al. Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine. Sci Rep. 2015 Sep 24;5:13730. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5250 mL | 7.6250 mL | 15.2499 mL | 38.1249 mL |
| 5 mM | 0.3050 mL | 1.5250 mL | 3.0500 mL | 7.6250 mL | |
| 10 mM | 0.1525 mL | 0.7625 mL | 1.5250 mL | 3.8125 mL | |
| 15 mM | 0.1017 mL | 0.5083 mL | 1.0167 mL | 2.5417 mL | |
| 20 mM | 0.0762 mL | 0.3812 mL | 0.7625 mL | 1.9062 mL | |
| 25 mM | 0.0610 mL | 0.3050 mL | 0.6100 mL | 1.5250 mL | |
| 30 mM | 0.0508 mL | 0.2542 mL | 0.5083 mL | 1.2708 mL | |
| 40 mM | 0.0381 mL | 0.1906 mL | 0.3812 mL | 0.9531 mL | |
| 50 mM | 0.0305 mL | 0.1525 mL | 0.3050 mL | 0.7625 mL | |
| 60 mM | 0.0254 mL | 0.1271 mL | 0.2542 mL | 0.6354 mL | |
| 80 mM | 0.0191 mL | 0.0953 mL | 0.1906 mL | 0.4766 mL | |
| 100 mM | 0.0152 mL | 0.0762 mL | 0.1525 mL | 0.3812 mL |
Ac-Nle-Pro-Nle-Asp-AMC Related Classifications
HY-P2016 Related Classifications
Powered by Bioz