2. Metabolic Enzyme/Protease
  3. Proteasome
  4. Ac-WLA-AMC

Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-WLA-AMC Chemical Structure

Ac-WLA-AMC Chemical Structure

CAS No. : 1104011-59-7

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1 mg USD 100 In-stock
5 mg USD 320 In-stock
10 mg USD 510 In-stock
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Based on 1 publication(s) in Google Scholar

Ac-WLA-AMC Related Antibodies

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Description

Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate[1].

IC50 & Target

20S constitutive proteasome β5[1]
Molecular Weight

587.67

Formula

C32H37N5O6
CAS No.
Appearance

Solid

Color

White to off-white

Emission (Em)

480
Excitation (Ex)

390
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (425.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7016 mL 8.5082 mL 17.0164 mL
5 mM 0.3403 mL 1.7016 mL 3.4033 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7016 mL 8.5082 mL 17.0164 mL 42.5409 mL
5 mM 0.3403 mL 1.7016 mL 3.4033 mL 8.5082 mL
10 mM 0.1702 mL 0.8508 mL 1.7016 mL 4.2541 mL
15 mM 0.1134 mL 0.5672 mL 1.1344 mL 2.8361 mL
20 mM 0.0851 mL 0.4254 mL 0.8508 mL 2.1270 mL
25 mM 0.0681 mL 0.3403 mL 0.6807 mL 1.7016 mL
30 mM 0.0567 mL 0.2836 mL 0.5672 mL 1.4180 mL
40 mM 0.0425 mL 0.2127 mL 0.4254 mL 1.0635 mL
50 mM 0.0340 mL 0.1702 mL 0.3403 mL 0.8508 mL
60 mM 0.0284 mL 0.1418 mL 0.2836 mL 0.7090 mL
80 mM 0.0213 mL 0.1064 mL 0.2127 mL 0.5318 mL
100 mM 0.0170 mL 0.0851 mL 0.1702 mL 0.4254 mL
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Ac-WLA-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-WLA-AMC1104011-59-7Proteasome20S constitutive proteasomefluorogenic substrateβ5 subunitInhibitorinhibitorinhibit

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