357275-54-8
Chemical Structure
(αS)-Lopinavir metabolite M-3/M-4
- No. CAS: 357275-54-8
- Formula:C37H48N4O6
- Molecular Weight:644.81
IUPAC Name: (2S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-2-(4-hydroxy-2-oxotetrahydropyrimidin-1(2H)-yl)-3-methylbutanamide
InChIKey: HECSHMHYHYDFLR-AILSMDFESA-N
SMILES: [C@@H](C(N[C@@H](CC1=CC=CC=C1)C[C@@H]([C@H](CC2=CC=CC=C2)NC(COC3=C(C)C=CC=C3C)=O)O)=O)([C@@H](C)C)N4C(=O)NC(O)CC4
Biological Activity: (αS)-Lopinavir metabolite M-3/M-4 is an HIV protease inhibitor with a Ki of 1.2 pM and antiviral activity against HIV. (αS)-Lopinavir metabolite M-3/M-4 inhibits HIV protease activity. (αS)-Lopinavir metabolite M-3/M-4 can be used for the research of human immunodeficiency virus (HIV) infection[1].
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(αS)-Lopinavir metabolite M-3/M-4 | (αS)-Lopinavir metabolite M-3/M-4 is an HIV protease inhibitor with a Ki of 1.2 pM and antiviral activity against HIV. (αS)-Lopinavir metabolite M-3/M-4 inhibits HIV protease activity. (αS)-Lopinavir metabolite M-3/M-4 can be used for the research of human immunodeficiency virus (HIV) infection. | |||||||||||||||||||||
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Keywords
