country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-W700110

Copy Link Print Information

(αS)-Lopinavir metabolite M-3/M-4

(αS)-Lopinavir metabolite M-3/M-4 is an HIV protease inhibitor with a K_i of 1.2 pM and antiviral activity against HIV. (αS)-Lopinavir metabolite M-3/M-4 inhibits HIV protease activity. (αS)-Lopinavir metabolite M-3/M-4 can be used for the research of human immunodeficiency virus (HIV) infection.

For research use only. We do not sell to patients.

CAS No.: 357275-54-8
Formula: C₃₇H₄₈N₄O₆
Molecular Weight:644.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(αS)-Lopinavir metabolite M-3/M-4 Chemical Structure

CAS No.: 357275-54-8

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

(αS)-Lopinavir metabolite M-3/M-4 inhibits HIV replication in MT-4 cells (in vitro in the presence of 50% human serum) with an EC₅₀ of 2.31 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 357275-54-8
Molecular Weight 644.81
Formula C₃₇H₄₈N₄O₆
SMILES

[C@@H](C(N[C@@H](CC1=CC=CC=C1)C[C@@H]([C@H](CC2=CC=CC=C2)NC(COC3=C(C)C=CC=C3C)=O)O)=O)([C@@H](C)C)N4C(=O)NC(O)CC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sham HL, et al. Synthesis and antiviral activities of the major metabolites of the HIV protease inhibitor ABT-378 (Lopinavir). Bioorganic & medicinal chemistry letters. 2001 Jun 04;11(11):1351-3. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote