365400-08-4
Chemical Structure
Oscillamide C
- CAS No.: 365400-08-4
- Formula:C49H68N10O10
- Molecular Weight:957.13
IUPAC Name: (((3S,6S,9S,12S,15R)-3-benzyl-12-((S)-sec-butyl)-6,9-bis(4-hydroxyphenethyl)-7-methyl-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclononadecan-15-yl)carbamoyl)-L-arginine
InChIKey: TTWROJJNRKDVPJ-FVCPQTOGSA-N
SMILES: OC(C=C1)=CC=C1CC[C@@H]2N(C([C@@H](NC([C@](NC([C@@H](CCCCNC([C@@H](NC2=O)CC3=CC=CC=C3)=O)NC(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)([H])[C@@H](C)CC)=O)CCC4=CC=C(C=C4)O)=O)C
Biological Activity: Oscillamide C (Compound 2), a ureido-containing cyclic peptide, is a Protein phosphatase 1 (PP1) and Protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.90 and 1.33 μM for PP1 and PP2A, respectively. Oscillamide C can be isolated from the cyanobacteria Planktothrix agardhii and P. rubescens. Oscillamide C can be used for cancers research[1].
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Oscillamide C | Oscillamide C (Compound 2), a ureido-containing cyclic peptide, is a Protein phosphatase 1 (PP1) and Protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.90 and 1.33 μM for PP1 and PP2A, respectively. Oscillamide C can be isolated from the cyanobacteria Planktothrix agardhii and P. rubescens. Oscillamide C can be used for cancers research. | |||||||||||||||||||||
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Keywords
