36556-75-9
Chemical Structure
Bucumolol hydrochloride
- CAS No.: 36556-75-9
- Formula:C17H24ClNO4
- Molecular Weight:341.83
IUPAC Name: 8-(3-(tert-butylamino)-2-hydroxypropoxy)-5-methyl-2H-chromen-2-one hydrochloride
InChIKey: OQVOZUWFVLLPRL-UHFFFAOYSA-N
SMILES: O=C1C=CC2=C(C=CC(OCC(CNC(C)(C)C)O)=C2O1)C.Cl
Biological Activity: Bucumolol hydrochloride is a β-adrenergic receptor antagonist that can slow heart rate (negative chronotropic effect) and reduce cardiac contractility (negative inotropic effect). Bucumolol hydrochloride has antiarrhythmic and local anesthetic activity and can be used in the study of cardiovascular diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Bucumolol hydrochloride | Bucumolol hydrochloride is a β-adrenergic receptor antagonist that can slow heart rate (negative chronotropic effect) and reduce cardiac contractility (negative inotropic effect). Bucumolol hydrochloride has antiarrhythmic and local anesthetic activity and can be used in the study of cardiovascular diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Nakayama, Koichi, et al. Antiarrhythmic activity of dextro-and levo-isomers OF 5-methyl-8-(2-hydroxy-3-t-butylamino-propoxy) coumarin hydrochloride (bucumolol), a β-adrenergic blocking agent, on aconitine-induced atrial and ouabain-induced ventricular arrhythmias in dogs. The Japanese Journal of Pharmacology 29.6 (1979): 935-945. [Content Brief]
Keywords
