374772-79-9
Chemical Structure
Bisphenol F bis(2-chloro-1-propanol) ether
Synonym(s): BFDGE·2HCl
- CAS No.: 374772-79-9
- Formula:C19H22Cl2O4
- Molecular Weight:385.28
IUPAC Name: (2-methoxy-4-methylphenyl)glycine
InChIKey: VAFXFEBPCUMOIF-UHFFFAOYSA-N
SMILES: ClC(COC1=CC=C(CC2=CC=C(C=C2)OCC(CO)Cl)C=C1)CO
Biological Activity: Bisphenol F bis(2-chloro-1-propanol) ether (BFDGE·2HCl) is an androgen receptor antagonist with a human IC50 of 18 μM. Bisphenol F bis(2-chloro-1-propanol) ether binds to the androgen receptor. Bisphenol F bis(2-chloro-1-propanol) ether (BFDGE·2HCl) can be used for research on hormonal activity[1][2].
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Bisphenol F bis(2-chloro-1-propanol) ether | Bisphenol F bis(2-chloro-1-propanol) ether (BFDGE·2HCl) is an androgen receptor antagonist with a human IC50 of 18 μM. Bisphenol F bis(2-chloro-1-propanol) ether binds to the androgen receptor. Bisphenol F bis(2-chloro-1-propanol) ether (BFDGE·2HCl) can be used for research on hormonal activity. | |||||||||||||||||||||
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- [1]. Satoh K, et al. Study on anti-androgenic effects of bisphenol a diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) and their derivatives using cells stably transfected with human androgen receptor, AR-EcoScreen. Food Chem Toxicol. 2004;42(6):983-993. [Content Brief]
- [2]. Zhang HL, et al. Urinary exposure level of emerging chemicals in Chinese pregnant women and their associations with oxidative stress. Emerg. Contam. 2015 Jun;11(2):100502.