384361-79-9
Chemical Structure
NPD926
- CAS No.: 384361-79-9
- Formula:C29H35ClN2O2
- Molecular Weight:479.05
IUPAC Name: 2-chloro-N-(4-(dimethylamino)benzyl)-N-(3-(4-isopropoxyphenyl)-3-phenylpropyl)acetamide
InChIKey: FRYFEHAKTZZMLQ-UHFFFAOYSA-N
SMILES: CC(OC1=CC=C(C=C1)C(C2=CC=CC=C2)CCN(CC3=CC=C(C=C3)N(C)C)C(CCl)=O)C
Biological Activity: NPD926 is a small molecule that targets glutathione and induces cancer cell death. NPD926 causes cellular glutathione depletion and subsequent generation of reactive oxygen species (ROS), thereby sensitizing fibroblasts to Xc- system inhibitors. NPD926 is a ROS inducer with anticancer activity.[1].
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NPD926 | NPD926 is a small molecule that targets glutathione and induces cancer cell death. NPD926 causes cellular glutathione depletion and subsequent generation of reactive oxygen species (ROS), thereby sensitizing fibroblasts to Xc- system inhibitors. NPD926 is a ROS inducer with anticancer activity.. | |||||||||||||||||||||
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Keywords
