394-31-0
Chemical Structure
5-Hydroxyanthranilic acid
- CAS No.: 394-31-0
- Formula:C7H7NO3
- Molecular Weight:153.14
IUPAC Name: 2-amino-5-hydroxybenzoic acid
InChIKey: HYNQTSZBTIOFKH-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC(O)=CC=C1N
Biological Activity: 5-Hydroxyanthranilic acid is a Tryptophan metabolite. 5-Hydroxyanthranilic acid activates the phosphorylation of p38 MAPK without activating Caspase-3. 5-Hydroxyanthranilic acid reduces methemoglobin to hemoglobin through electron transfer, thereby achieving the formation of oxygenated hemoglobin, and reduces methemoglobin under aerobic conditions through the generation of hemoglobin. 5-Hydroxyanthranilic acid can be used in research on neurological diseases[1][2].
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5-Hydroxyanthranilic acid | 99.85% | 5-Hydroxyanthranilic acid is a Tryptophan metabolite. 5-Hydroxyanthranilic acid activates the phosphorylation of p38 MAPK without activating Caspase-3. 5-Hydroxyanthranilic acid reduces methemoglobin to hemoglobin through electron transfer, thereby achieving the formation of oxygenated hemoglobin, and reduces methemoglobin under aerobic conditions through the generation of hemoglobin. 5-Hydroxyanthranilic acid can be used in research on neurological diseases. | ||||||||||||||||||||
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References
- [1]. Smith AJ, et al. 5-Hydroxyanthranilic acid, a tryptophan metabolite, generates oxidative stress and neuronal death via p38 activation in cultured cerebellar granule neurones. Neurotoxicity research. 2009 May;15(4):303-10.
- [2]. Goda , et al. Kinetic studies of the reduction of methemoglobin by 5-hydroxyanthranilic acid, tryptophan metabolite. Biochem Biophys Res Commun. 1977 Oct 24;78(4):1198-203. [Content Brief]
