4152-77-6
4152-77-6
Chemical Structure
KIN59
Synonym(s): 5'-O-Tritylinosine; 5'-O-Trityl-inosine
- CAS No.: 4152-77-6
- Formula:C29H26N4O5
- Molecular Weight:510.54
IUPAC Name: (2R,3R,4S,5R)-2-(6-hydroxy-9H-purin-9-yl)-5-((trityloxy)methyl)tetrahydrofuran-3,4-diol
InChIKey: YEPZMZDCXFRHCL-ZYWWQZICSA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6
Biological Activity: KIN59 (5’-O-Tritylinosine) is a potent thymidine phosphorylase allosteric inhibitor. KIN59 inhibits FGF2-stimulated cell growth. KIN59 inhibits the expression of p-FGFR1, P-Akt in FGF2 (10 ng/mL) stimulated cells. KIN59 shows anti-tumor activity[1].
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KIN59 | 99.0% | KIN59 (5’-O-Tritylinosine) is a potent thymidine phosphorylase allosteric inhibitor. KIN59 inhibits FGF2-stimulated cell growth. KIN59 inhibits the expression of p-FGFR1, P-Akt in FGF2 (10 ng/mL) stimulated cells. KIN59 shows anti-tumor activity. | ||||||||||||||||||||
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KIN59 (Standard) | ≥98% | KIN59 (Standard) is the analytical standard of KIN59 (HY-102071). This product is intended for research and analytical applications. KIN59 (5’-O-Tritylinosine) is a potent thymidine phosphorylase allosteric inhibitor. KIN59 inhibits FGF2-stimulated cell growth. KIN59 inhibits the expression of p-FGFR1, P-Akt in FGF2 (10 ng/mL) stimulated cells. KIN59 shows anti-tumor activity. | ||||||||||||||||||||
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