41600-13-9
41600-13-9
Chemical Structure
AMPte-Glu-γ-Glu
- CAS No.: 41600-13-9
- Formula:C25H29N9O8
- Molecular Weight:583.55
IUPAC Name: ((S)-4-carboxy-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)butanoyl)-L-glutamic acid
InChIKey: PIHMDTSRKDVWKE-HOTGVXAUSA-N
SMILES: O=C(CC[C@H](NC(CC[C@H](NC(C1=CC=C(C=C1)N(C)CC2=NC3=C(N=C(N=C3N=C2)N)N)=O)C(O)=O)=O)C(O)=O)O
Biological Activity: AMPte-Glu-γ-Glu is a substrate for folylpoly-γ-glutamate synthetase (FPGS). AMPte-Glu-γ-Glu exhibits cytotoxicity against chinese hamster ovaries cells, with IC50s of 20, 350 and 3 nM, for Pro3, R2, and 43-10, respectively[1].
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AMPte-Glu-γ-Glu | AMPte-Glu-γ-Glu is a substrate for folylpoly-γ-glutamate synthetase (FPGS). AMPte-Glu-γ-Glu exhibits cytotoxicity against chinese hamster ovaries cells, with IC50s of 20, 350 and 3 nM, for Pro3, R2, and 43-10, respectively. | |||||||||||||||||||||
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References
Keywords
