422276-47-9

EGFR/HER2/CDK9-IN-3 Chemical Structure
422276-47-9

Chemical Structure

EGFR/HER2/CDK9-IN-3

  • CAS No.: 422276-47-9
  • Formula:C24H21N3O4S2
  • Molecular Weight:479.57

IUPAC Name: 4-(2-(4-oxo-2-((2-oxo-2-phenylethyl)thio)quinazolin-3(4H)-yl)ethyl)benzenesulfonamide

InChIKey: ZTSOUXIIJZKOEJ-UHFFFAOYSA-N

SMILES: O=S(C1=CC=C(CCN2C(SCC(C3=CC=CC=C3)=O)=NC4=C(C=CC=C4)C2=O)C=C1)(N)=O

Biological Activity: EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 191.08, 132.65, and 113.98 nM, respectively. EGFR/HER2/CDK9-IN-3 exhibits remarkable antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-147798 		EGFR/HER2/CDK9-IN-3 EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 191.08, 132.65, and 113.98 nM, respectively. EGFR/HER2/CDK9-IN-3 exhibits remarkable antitumor activity.
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