465-74-7
Chemical Structure
Quinovic acid
- CAS No.: 465-74-7
- Formula:C30H46O5
- Molecular Weight:486.68
IUPAC Name: (1S,2R,4aS,6aR,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-1,2,6b,9,9,12a-hexamethyl-1,2,3,4,5,6,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a,6a-dicarboxylic acid
InChIKey: OJUYFGQEMPENCE-DPKHZRJYSA-N
SMILES: OC([C@@]12C([C@@]3([H])[C@@](CC2)(CC[C@H]([C@@H]3C)C)C(O)=O)=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(CC[C@@H](C5(C)C)O)C)C)=O
Biological Activity: Quinovic acid is triterpene. Quinovic acid can ameliorate the Amyloid-β burden, p53 expression and cholesterol accumulation by deterring the oxidative stress through upregulating the Nrf2/HO-1 pathway. Quinovic acid can induce cancer cells apoptosis by upregulating death receptor 5 (DR5). Quinovic acid can be used for the researches of cancer, inflammation, metabolic and neurological disease, such as lung cancer and Alzheimer’s disease (AD)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Quinovic acid | 96.0% | Quinovic acid is triterpene. Quinovic acid can ameliorate the Amyloid-β burden, p53 expression and cholesterol accumulation by deterring the oxidative stress through upregulating the Nrf2/HO-1 pathway. Quinovic acid can induce cancer cells apoptosis by upregulating death receptor 5 (DR5). Quinovic acid can be used for the researches of cancer, inflammation, metabolic and neurological disease, such as lung cancer and Alzheimer’s disease (AD). | ||||||||||||||||||||
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- [1]. Saeed K, et al. Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model. Oxid Med Cell Longev. 2020 Nov 20;2020:9523758. [Content Brief]
- [2]. Khayam AU, et al. Quinovic acid purified from medicinal plant Fagonia indica mediates anticancer effects via death receptor 5. Mol Cell Biochem. 2020 Nov;474(1-2):159-169. [Content Brief]
Keywords
