470704-11-1
470704-11-1
Chemical Structure
2F5 epitope
- CAS No.: 470704-11-1
- Formula:C76H113N17O22
- Molecular Weight:1616.81
SMILES: [ELLELDKWASLWN]
Biological Activity: 2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2].
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2F5 epitope | 2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5. | |||||||||||||||||||||
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References
- [1]. Zohar Biron, et al. A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41. Biochemistry. 2002 Oct 22;41(42):12687-96. [Content Brief]
- [2]. Yougang Zhai, et al. Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 4;31(46):5422-9. [Content Brief]
