473728-04-0
Chemical Structure
CXCR2/CCR7 antagonist-1
- CAS No.: 473728-04-0
- Formula:C23H27N3O5
- Molecular Weight:425.48
SMILES: OC1=C(C(N(C)C)=O)C=CC=C1NC2=C(N[C@H](C(C)(C)C)C3=CC=C(C)O3)C(C2=O)=O
Biological Activity: CXCR2/CCR7 antagonist-1 (compound 6) is a potent CXCR2 and CCR7 dual antagonist with IC50s of 0.0046 and 0.0014 μM, respectively. CXCR2/CCR7 antagonist-1 can be used in the study of cancer metastasis and autoimmune diseases[1].
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CXCR2/CCR7 antagonist-1 | CXCR2/CCR7 antagonist-1 (compound 6) is a potent CXCR2 and CCR7 dual antagonist with IC50s of 0.0046 and 0.0014 μM, respectively. CXCR2/CCR7 antagonist-1 can be used in the study of cancer metastasis and autoimmune diseases. | |||||||||||||||||||||
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Keywords