4749-61-5
4749-61-5
Chemical Structure
ST91
- CAS 番号: 4749-61-5
- Formula:C13H20ClN3
- Molecular Weight:253.77
IUPAC Name: N-(2,6-diethylphenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride
InChIKey: ZLRWFGBEDNTMEU-UHFFFAOYSA-N
SMILES: CCC1=C(NC2=NCCN2)C(CC)=CC=C1.Cl
Biological Activity: ST91 is a α2-adrenoceptor (α2AR) agonist. ST91 activates both α2AAR and non-α2AAR subtypes to produce spinal antinociception[1][2][3].
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ST91 | 99.75% | ST91 is a α2-adrenoceptor (α2AR) agonist. ST91 activates both α2AAR and non-α2AAR subtypes to produce spinal antinociception. | ||||||||||||||||||||
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ST91 (Standard) | ≥98% | ST91 (Standard) is the analytical standard of ST91 (HY-103203). This product is intended for research and analytical applications. ST91 is a α2-adrenoceptor (α2AR) agonist. ST91 activates both α2AAR and non-α2AAR subtypes to produce spinal antinociception. | ||||||||||||||||||||
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References
- [1]. Graham BA, et, al. Synergistic interactions between two alpha(2)-adrenoceptor agonists, dexmedetomidine and ST-91, in two substrains of Sprague-Dawley rats. Pain. 2000 Mar;85(1-2):135-43. [Content Brief]
- [2]. Maccari S, et, al. α-Adrenoceptor stimulation attenuates melanoma growth in mice. Br J Pharmacol. 2022 Apr;179(7):1371-1383. [Content Brief]
- [3]. Stone LS, et, al. ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors. J Pharmacol Exp Ther. 2007 Dec;323(3):899-906. [Content Brief]
Keywords
