474943-05-0
474943-05-0
Chemical Structure
C12-NBD Sphinganine
- CAS No.: 474943-05-0
- Formula:C36H63N5O6
- Molecular Weight:661.92
IUPAC Name: N-((2S,3R)-1,3-dihydroxyoctadecan-2-yl)-12-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)dodecanamide
InChIKey: STPDREBSVHTICB-CQTOTRCISA-N
SMILES: CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(CCCCCCCCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O
Biological Activity: C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources[1][2][3].
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C12-NBD Sphinganine | 99.9% | C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources. | ||||||||||||||||||||
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References
- [1]. Rigogliuso S, et al. An active form of sphingosine kinase-1 is released in the extracellular medium as component of membrane vesicles shed by two human tumor cell lines. J Oncol. 2010;2010:509329. [Content Brief]
- [2]. Okino N, et al. Expression, purification, and characterization of a recombinant neutral ceramidase from Mycobacterium tuberculosis. Biosci Biotechnol Biochem. 2010;74(2):316-21. [Content Brief]
- [3]. Vijai Kumar Reddy T, et al. Design, synthesis and in vitro biological evaluation of short-chain C12-sphinganine and its 1,2,3-triazole analogs as potential antimicrobial and anti-biofilm agents. Eur J Med Chem. 2016 Aug 8;118:98-106. [Content Brief]
Keywords
