474949-70-7
Chemical Structure
S 3578 sulfate
- CAS No.: 474949-70-7
- Formula:C24H30N10O9S3
- Molecular Weight:698.75
IUPAC Name: 4-(((6R,7R)-7-((Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-(3-(methylamino)propyl)-1H-imidazo[4,5-b]pyridin-4-ium hydrogen sulfate
InChIKey: VUPJGETUYIIPNC-UHMSALISSA-N
SMILES: [O-]S(=O)(O)=O.OC(C1=C(C[N+]2=C3C(N(CCCNC)C=N3)=CC=C2)CS[C@@]([C@@H]4NC(/C(C5=NSC(N)=N5)=N\OCC)=O)([H])N1C4=O)=O
Biological Activity: S 3578 sulfate is a broad-spectrum antibacterial agent, particularly effective against methicillin-resistant Staphylococcus aureus (MRSA) (MIC = 0.78-3.13 μg/mL) and Pseudomonas aeruginosa (MIC = 1.56-6.25 μg/mL). S 3578 sulfate can be used in the research of infectious conditions[1].
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S 3578 sulfate | S 3578 sulfate is a broad-spectrum antibacterial agent, particularly effective against methicillin-resistant Staphylococcus aureus (MRSA) (MIC = 0.78-3.13 μg/mL) and Pseudomonas aeruginosa (MIC = 1.56-6.25 μg/mL). S 3578 sulfate can be used in the research of infectious conditions. | |||||||||||||||||||||
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References
- [1]. Yoshizawa H, et al. New broad-spectrum parenteral cephalosporins exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Part 2: Synthesis and structure-activity relationships in the S-3578 series. Bioorg Med Chem. 2004 Aug 1;12(15):4211-9. [Content Brief]
