4753-04-2
4753-04-2
Chemical Structure
2′-Chloro-2′-deoxyuridine
- CAS No.: 4753-04-2
- Formula:C9H11ClN2O5
- Molecular Weight:262.65
IUPAC Name: 1-((2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: XOTUXDQKWDTKSI-XVFCMESISA-N
SMILES: O[C@H]1[C@@H](Cl)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO
Biological Activity: 2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2′-Chloro-2′-deoxyuridine | 2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
