4784-40-1
4784-40-1
Chemical Structure
Oxomemazine hydrochloride
- CAS No.: 4784-40-1
- Formula:C18H23ClN2O2S
- Molecular Weight:366.91
InChIKey: NPMMOYKGIWLASW-UHFFFAOYSA-N
SMILES: O=S1(C2=C(N(CC(CN(C)C)C)C3=C1C=CC=C3)C=CC=C2)=O.Cl
Biological Activity: Oxomemazine hydrochloride is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine hydrochloride is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (Ki= 84 nM, M1 receptor) and low (Ki= 1.65 μM, M2 receptor) affinity sites[1]. Oxomemazine hydrochloride an antihistamine and anticholinergic agent used for the study of cough treatment[2].
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Oxomemazine hydrochloride | Oxomemazine hydrochloride is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine hydrochloride is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (Ki= 84 nM, M1 receptor) and low (Ki= 1.65 μM, M2 receptor) affinity sites. Oxomemazine hydrochloride an antihistamine and anticholinergic agent used for the study of cough treatment. | |||||||||||||||||||||
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