480-93-3
480-93-3
Chemical Structure
3-Hydroxyindole
- CAS No.: 480-93-3
- Formula:C8H7NO
- Molecular Weight:133.15
IUPAC Name: 1H-indol-3-ol
InChIKey: PCKPVGOLPKLUHR-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=CN2)O
Biological Activity: 3-Hydroxyindole is a hydroxyindole compound. 3-Hydroxyindole can be isolated from the fruits of Aristotelia chilensis. 3-Hydroxyindole inhibits Ferroptosis and scavenges DPPH free radicals. 3-Hydroxyindole protects against β-amyloid-induced toxicity. 3-Hydroxyindole exhibits antioxidant activity. 3-Hydroxyindole can be used in research related to neurodegenerative diseases[1][2][3].
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3-Hydroxyindole | 87.60% | 3-Hydroxyindole is a hydroxyindole compound. 3-Hydroxyindole can be isolated from the fruits of Aristotelia chilensis. 3-Hydroxyindole inhibits Ferroptosis and scavenges DPPH free radicals. 3-Hydroxyindole protects against β-amyloid-induced toxicity. 3-Hydroxyindole exhibits antioxidant activity. 3-Hydroxyindole can be used in research related to neurodegenerative diseases. | ||||||||||||||||||||
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References
- [1]. Céspedes CL, et al. Antioxidant activity of an unusual 3-hydroxyindole derivative isolated from fruits of Aristotelia chilensis (Molina) Stuntz. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2009;64(9-10):759-62. [Content Brief]
- [2]. Jakaria M, et al. The role of hydroxyindoles in protecting neuronal cultures from ferroptosis. Cell death discovery. 2025 Jul 16;11(1):329. [Content Brief]
- [3]. Jakaria M, et al. Inhibition of Ferroptotic Toxicity by 4-Hydroxyindole. Chemical research in toxicology. 2025 Nov 17;38(11):2002-2009.
