483-14-7
483-14-7
Chemical Structure
Rotundine
Synonym(s): (-)-Tetrahydropalmatine; L-Tetrahydropalmatine
- CAS No.: 483-14-7
- Formula:C21H25NO4
- Molecular Weight:355.43
IUPAC Name: (S)-2,3,9,10-tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline
InChIKey: AEQDJSLRWYMAQI-KRWDZBQOSA-N
SMILES: COC1=CC=C2C(CN3CCC4=CC(OC)=C(OC)C=C4[C@]3([H])C2)=C1OC
Biological Activity: Rotundine is an antagonist of dopamine D1, D2 and D3 receptors with IC50s of 166 nM, 1.4 μM and 3.3 μM, respectively. Rotundine is also an antagonist of 5-HT1A with an IC50 of 370 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Rotundine | 99.96% | Rotundine is an antagonist of dopamine D1, D2 and D3 receptors with IC50s of 166 nM, 1.4 μM and 3.3 μM, respectively. Rotundine is also an antagonist of 5-HT1A with an IC50 of 370 nM. | ||||||||||||||||||||
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