491845-95-5
491845-95-5
Chemical Structure
RY764
- CAS. Nr.: 491845-95-5
- Formula:C34H51FN4O3
- Molecular Weight:582.79
IUPAC Name: (1R,4S,6R)-N-((R)-1-(4-(tert-butylcarbamoyl)-4-cyclohexylpiperidin-1-yl)-3-(4-fluorophenyl)-1-oxopropan-2-yl)-2-methyl-2-azabicyclo[2.2.2]octane-6-carboxamide
InChIKey: ARFBDECCXOFCBN-HOLBEBDISA-N
SMILES: CC(C)(C)NC(C1(C2CCCCC2)CCN(CC1)C([C@H](NC([C@H]3[C@]4([H])N(C[C@](CC4)([H])C3)C)=O)CC5=CC=C(C=C5)F)=O)=O
Biological Activity: RY746 is a selective MC4R agonist, with an EC50 of 10 nM. RY764 effectively inhibits food intake and reduces body weight gain in diet-induced obese (DIO) rat models. RY764 can be used for the study of obesity[1].
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RY764 | RY746 is a selective MC4R agonist, with an EC50 of 10 nM. RY764 effectively inhibits food intake and reduces body weight gain in diet-induced obese (DIO) rat models. RY764 can be used for the study of obesity. | |||||||||||||||||||||
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