49555-43-3
Chemical Structure
5-Methyl-4-thiouridine
- CAS No.: 49555-43-3
- Formula:C10H14N2O5S
- Molecular Weight:274.29
IUPAC Name: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
InChIKey: IXDWFVOGUMAKFI-JXOAFFINSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(C(C)=C2)=S)=O)O1
Biological Activity: 5-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-Methyl-4-thiouridine | 5-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
