496793-78-3
496793-78-3
Chemical Structure
Methoxy-SANT-2
Synonym(s): TC-132
- CAS No.: 496793-78-3
- Formula:C23H20ClN3O4
- Molecular Weight:437.88
IUPAC Name: N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-3,4,5-trimethoxybenzamide
InChIKey: WPVPAGJUOPBMCZ-UHFFFAOYSA-N
SMILES: COC1=C(C(OC)=CC(C(NC2=CC(C3=NC4=C(N3)C=CC=C4)=C(C=C2)Cl)=O)=C1)OC
Biological Activity: Methoxy-SANT-2 (TC-132) is a potent hedgehog antagonist with an IC50 value of 79.8 nM. Methoxy-SANT-2 inhibits the Gli1 reporter gene expression. Methoxy-SANT-2 has the potential for the research of cancer[1].
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Methoxy-SANT-2 | Methoxy-SANT-2 (TC-132) is a potent hedgehog antagonist with an IC50 value of 79.8 nM. Methoxy-SANT-2 inhibits the Gli1 reporter gene expression. Methoxy-SANT-2 has the potential for the research of cancer. | |||||||||||||||||||||
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Keywords
