503048-34-8
503048-34-8
Chemical Structure
JTK-101
- CAS No.: 503048-34-8
- Formula:C25H23N3O3
- Molecular Weight:413.47
IUPAC Name: 4-((9-methoxy-4-oxo-3,4-dihydrospiro[naphtho[2,1-e][1,3]oxazine-2,4'-piperidin]-1'-yl)methyl)benzonitrile
InChIKey: IFFDMBLMXJBGLL-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(C=C1)CN2CCC(CC2)(OC3=C4C=C(C=CC4=CC=C35)OC)NC5=O
Biological Activity: JTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research[1].
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JTK-101 | JTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research. | |||||||||||||||||||||
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References
Keywords
