50656-65-0
50656-65-0
Chemical Structure
Rotundifuran
- CAS No.: 50656-65-0
- Formula:C22H34O4
- Molecular Weight:362.50
IUPAC Name: (1R,3R,4R,4aS,8aS)-4-(2-(furan-3-yl)ethyl)-4-hydroxy-3,4a,8,8-tetramethyldecahydronaphthalen-1-yl acetate
InChIKey: QKHCQFQIJKXMOE-UGFIEOPBSA-N
SMILES: O[C@]1(CCC2=COC=C2)[C@H](C)C[C@@H](OC(C)=O)[C@@]3([H])C(C)(C)CCC[C@]13C
Biological Activity: Rotundifuran, a labdane type diterpene, is isolated from Vitex rotundifolia. Rotundifuran can inhibit the cell cycle progression and induce apoptosis in human myeloid leukaemia cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Rotundifuran | 98.74% | Rotundifuran, a labdane type diterpene, is isolated from Vitex rotundifolia. Rotundifuran can inhibit the cell cycle progression and induce apoptosis in human myeloid leukaemia cells. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.73
HY-N6995RMarrubiin (Standard) -
Similarity Score 0.66
HY-N8271Galeopsin -
Similarity Score 0.59
HY-N93078-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione -
Similarity Score 0.59
HY-N9307A(S)-8-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione -
Similarity Score 0.58
HY-N9730Methyl 2α-hydroxyhardwickiate -
Similarity Score 0.58
HY-N15291Divinatorin A -
Similarity Score 0.58
HY-N197668α-Hydroxyhardwickiic acid -
Similarity Score 0.57
HY-N90816β-Hydroxyhispanone -
Similarity Score 0.57
HY-N91676α-Hydroxyhispanone -
Explore the MedChemAI to find more analogs
References
- [1]. Ko WG, et, al. Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells. Phytother Res. 2001 Sep; 15(6):535-7. [Content Brief]
- [2]. Li WX, et, al. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res. 2005 Apr; 7(2): 95-105. [Content Brief]
