52940-67-7
Chemical Structure
N1-Methyl-GTP
- CAS No.: 52940-67-7
- Formula:C11H18N5O14P3
- Molecular Weight:537.21
InChIKey: YWHNPOKVSACYOQ-KQYNXXCUSA-N
SMILES: O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O3)=C2N=C(N)N1C
Biological Activity: N1-Methyl-GTP is a nucleotide analog of GTP. N1-Methyl-GTP shows a half-maximal inhibitory concentration of 8.1 μM and an inhibition constant of 1.5 μM against yeast RTPase. N1-Methyl-GTP can be used as a probe molecule to explore the structural flexibility of the active site of RNA triphosphatase and the mechanism of substrate recognition[1].
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N1-Methyl-GTP | N1-Methyl-GTP is a nucleotide analog of GTP. N1-Methyl-GTP shows a half-maximal inhibitory concentration of 8.1 μM and an inhibition constant of 1.5 μM against yeast RTPase. N1-Methyl-GTP can be used as a probe molecule to explore the structural flexibility of the active site of RNA triphosphatase and the mechanism of substrate recognition. | |||||||||||||||||||||
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Keywords