53100-44-0
53100-44-0
Chemical Structure
Boc-Pyr-OH
Synonym(s): N-Boc-L-pyroglutamic acid
- CAS No.: 53100-44-0
- Formula:C10H15NO5
- Molecular Weight:229.23
IUPAC Name: (S)-1-(tert-butoxycarbonyl)-5-oxopyrrolidine-2-carboxylic acid
InChIKey: MJLQPFJGZTYCMH-LURJTMIESA-N
SMILES: O=C(N1[C@H](C(O)=O)CCC1=O)OC(C)(C)C
Biological Activity: Boc-Pyr-OH (N-Boc-L-pyroglutamic acid) is an N-Boc-protected L-pyroglutamic acid derivative. Boc-Pyr-OH serves as a synthetic intermediate for the preparation of peptides containing lactam-type amino acids[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Boc-Pyr-OH | 98.0% | Boc-Pyr-OH (N-Boc-L-pyroglutamic acid) is an N-Boc-protected L-pyroglutamic acid derivative. Boc-Pyr-OH serves as a synthetic intermediate for the preparation of peptides containing lactam-type amino acids. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-41631Boc-Pyr-Oet -
Similarity Score 0.83
HY-W003605Boc-D-Pyr-Oet -
Similarity Score 0.83
HY-W003605A1-Boc-DL-Pyroglutamic acid ethyl ester -
Similarity Score 0.75
HY-W007743Boc-Pip-OH -
Similarity Score 0.75
HY-W013473Boc-D-HoPro-OH -
Similarity Score 0.74
HY-W019205(4S)-1-Boc-4-amino-D-proline -
Similarity Score 0.74
HY-77593(2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid -
Similarity Score 0.74
HY-I0781Boc-Hyp-OH -
Similarity Score 0.74
HY-W002886N-Boc-cis-4-hydroxy-L-proline -
Explore the MedChemAI to find more analogs
References
- [1]. Yoshifuji S, et al. A Novel Synthesis of L-Pyroglutamic Acid Derivatives from L-Proline : Utility of N-Protecting Groups for Ruthenium Tetroxide Oxidation of Cyclic α-Amino Acids. Chemical and Pharmaceutical Bulletin, 1986, 34(9): 3873-3878.
- [2]. Shirako S, et al. Pyroglutamyl leucine, a peptide in fermented foods, attenuates dysbiosis by increasing host antimicrobial peptide. NPJ science of food. 2019;3:18. [Content Brief]
