53760-19-3
Chemical Structure
Cytochalasin H
- CAS No.: 53760-19-3
- Formula:C30H39NO5
- Molecular Weight:493.63
IUPAC Name: (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-1-oxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate
InChIKey: NAEWXXDGBKTIMN-OWTACEMYSA-N
SMILES: O=C([C@@]12[C@](/C=C/C[C@H](C)C[C@@](C)(O)/C=C/[C@H]2OC(C)=O)([H])[C@@H]3O)N[C@@H](CC4=CC=CC=C4)[C@]1([H])[C@H](C)C3=C
Biological Activity: Cytochalasin H is a nature product that could be isolated from fungus Phomopsis sp. Cytochalasin H inhibits cell growth and induces apoptosis. Cytochalasin H has anti-angiogenic activity. Cytochalasin H is an antibiotic and has antibacterial activity[1][2][3].
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Cytochalasin H | 99.40% | Cytochalasin H is a nature product that could be isolated from fungus Phomopsis sp. Cytochalasin H inhibits cell growth and induces apoptosis. Cytochalasin H has anti-angiogenic activity. Cytochalasin H is an antibiotic and has antibacterial activity. | ||||||||||||||||||||
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- [1]. Ma Y, et, al. Cytochalasin H isolated from mangrove‑derived endophytic fungus induces apoptosis and inhibits migration in lung cancer cells. Oncol Rep. 2018 Jun;39(6):2899-2905. [Content Brief]
- [2]. Yi JM, et, al. In Vivo Anti-tumor Effects of the Ethanol Extract of Gleditsia sinensis Thorns and Its Active Constituent, Cytochalasin H. Biol Pharm Bull. 2015;38(6):909-12. [Content Brief]
- [3]. Jouda JB, et, al. Antibacterial and cytotoxic cytochalasins from the endophytic fungus Phomopsis sp. harbored in Garcinia kola (Heckel) nut. BMC Complement Altern Med. 2016 Nov 14;16(1):462. [Content Brief]
Keywords