53823-15-7
Chemical Structure
Tenellin
- CAS No.: 53823-15-7
- Formula:C21H23NO5
- Molecular Weight:369.41
IUPAC Name: 3-((R,2E,4E)-4,6-dimethylocta-2,4-dienoyl)-1,4-dihydroxy-5-(4-hydroxyphenyl)pyridin-2(1H)-one
InChIKey: YELFBSBOFKWHSL-UCFWAISOSA-N
SMILES: O=C1C(C(/C=C/C(C)=C/[C@H](C)CC)=O)=C(O)C(C2=CC=C(O)C=C2)=CN1O
Biological Activity: Tenellin is a fungal metabolite that has been found in Beauveria. It inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes by 51, 57, and 74%, respectively, when used at a concentration of 200 μg/mL.1 Tenellin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of- 4.84 and 11.95 μM, respectively.
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Tenellin | Tenellin is a fungal metabolite that has been found in Beauveria. It inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes by 51, 57, and 74%, respectively, when used at a concentration of 200 μg/mL.1 Tenellin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of- 4.84 and 11.95 μM, respectively. | |||||||||||||||||||||
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