53868-26-1
Chemical Structure
(Rac)-NSC305787 hydrochloride
- CAS No.: 53868-26-1
- Formula:C25H31Cl3N2O
- Molecular Weight:481.89
IUPAC Name: (2-((3r,5r,7r)-adamantan-1-yl)-6,8-dichloroquinolin-4-yl)(piperidin-2-yl)methanol hydrochloride
InChIKey: JQALIVSYOXLOBE-YIRSMLJJSA-N
SMILES: OC(C1CCCCN1)C2=CC(C3(C[C@H](C4)C5)C[C@H]5C[C@H]4C3)=NC(C(Cl)=C6)=C2C=C6Cl.[H]Cl
Biological Activity: NSC305787 hydrochloride is an inhibitor of ezrin with a Kd of 5.85 μM, inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50 of 8.3 μM, has antitumor activity.
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(Rac)-NSC305787 hydrochloride | 98.18% | NSC305787 hydrochloride is an inhibitor of ezrin with a Kd of 5.85 μM, inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50 of 8.3 μM, has antitumor activity. | ||||||||||||||||||||
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Keywords