54245-10-2
54245-10-2
Chemical Structure
D715-2441
- CAS No.: 54245-10-2
- Formula:C13H8O4
- Molecular Weight:228.20
IUPAC Name: 1,3-dihydroxy-6H-benzo[c]chromen-6-one
InChIKey: VLXAGAKGJMXVQF-UHFFFAOYSA-N
SMILES: O=C1C2=CC=CC=C2C3=C(O)C=C(O)C=C3O1
Biological Activity: D715-2441 is an influenza virus RNA polymerase inhibitor (IC50=1.7-4.4 μM). D715-2441 exhibits broad-spectrum antiviral activity against multiple influenza A strains. D715-2441 is promising for research of seasonal influenza and influenza viruses[1][2].
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D715-2441 | D715-2441 is an influenza virus RNA polymerase inhibitor (IC50=1.7-4.4 μM). D715-2441 exhibits broad-spectrum antiviral activity against multiple influenza A strains. D715-2441 is promising for research of seasonal influenza and influenza viruses. | |||||||||||||||||||||
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References
- [1]. Liu T, et al. A Small-Molecule Compound Has Anti-influenza A Virus Activity by Acting as a ''PB2 Inhibitor". Mol Pharm. 2018 Sep 4;15(9):4110-4120. [Content Brief]
- [2]. Giacchello I, et al. Insights into RNA-dependent RNA Polymerase Inhibitors as Antiinfluenza Virus Agents. Curr Med Chem. 2021;28(6):1068-1090. [Content Brief]
Keywords
