5429-85-6
5429-85-6
Chemical Structure
Oleyl anilide
Synonym(s): Oleic acid anilide; OAA
- CAS. Nr.: 5429-85-6
- Formula:C24H39NO
- Molecular Weight:357.57
IUPAC Name: N-phenyloleamide
InChIKey: YPUOCYKJOLQYQS-KTKRTIGZSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(NC1=CC=CC=C1)=O
Biological Activity: Oleyl anilide (Oleic acid anilide) is a toxic agent found in some stocks of toxic oil, which is associated with toxic oil syndrome (TOS). Oleyl anilide is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT) (IC50: 26 µM)[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Oleyl anilide | 95.2% | Oleyl anilide (Oleic acid anilide) is a toxic agent found in some stocks of toxic oil, which is associated with toxic oil syndrome (TOS). Oleyl anilide is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT) (IC50: 26 µM). | ||||||||||||||||||||
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References
- [1]. Roth BD, et al. Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents. J Med Chem. 1992 May 1;35(9):1609-17. [Content Brief]
- [2]. Cai P, et al. Immunotoxic response of oleic acid anilide and its hydrolysis products in female MRL (+/+) mice. J Immunotoxicol. 2005 Oct 1;2(4):231-6. [Content Brief]
