544686-20-6
544686-20-6
Chemical Structure
Celecoxib-d4
- CAS No.: 544686-20-6
- Formula:C17H10D4F3N3O2S
- Molecular Weight:385.40
IUPAC Name: 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzene-2,3,5,6-d4-sulfonamide
InChIKey: RZEKVGVHFLEQIL-YKVCKAMESA-N
SMILES: FC(F)(C1=NN(C2=C([2H])C([2H])=C(C([2H])=C2[2H])S(N)(=O)=O)C(C3=CC=C(C=C3)C)=C1)F
Biological Activity: Celecoxib-d4 is the deuterium labeled Desmethyl Celecoxib. Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an?analog?of Celecoxib and with the optimal yield of 75%[1].
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Celecoxib-d4 | Celecoxib-d4 is the deuterium labeled Desmethyl Celecoxib. Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an?analog?of Celecoxib and with the optimal yield of 75%. | |||||||||||||||||||||
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Celecoxib (GMP Like) | Celecoxib (SC 58635) GMP Like is a GMP-class Celecoxib (HY-14398). Celecoxib, a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM. | |||||||||||||||||||||
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Celecoxib (GMP) | Celecoxib (GMP) is Celecoxib (HY-14398) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM. | |||||||||||||||||||||
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Celecoxib (Standard) | 99.97% | Celecoxib (Standard) is the analytical standard of Celecoxib. This product is intended for research and analytical applications. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM. | ||||||||||||||||||||
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Celecoxib-d3 | 99.0% | Celecoxib-d3 is the deuterium labeled Celecoxib. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM. | ||||||||||||||||||||
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Celecoxib-d7 | 99.58% | Celecoxib-d7 is the deuterium labeled Celecoxib. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM. | ||||||||||||||||||||
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Celecoxib | 99.97% | Celecoxib,a selective and BBB-permeable non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM. | ||||||||||||||||||||
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References
