545-84-6

(−)-Voacangarine Chemical Structure
545-84-6

Chemical Structure

(−)-Voacangarine

  • CAS No.: 545-84-6
  • Formula:C22H28N2O4
  • Molecular Weight:384.47

IUPAC Name: methyl (6S,6aS,7S,9R,11S)-7-((S)-1-hydroxyethyl)-2-methoxy-7,8,9,10,12,13-hexahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-6(6aH)-carboxylate

InChIKey: OYMQKBZMKFJPMH-VJMPXSKLSA-N

SMILES: O=C([C@@]1([C@@]([C@@](C2)([H])[C@@H](O)C)([H])[N@@]3C[C@@]2([H])C1)C4=C(CC3)C5=CC(OC)=CC=C5N4)OC

Biological Activity: (−)-Voacangarine is an indole alkaloid, which exhibits cytotoxic effects against cancer cells HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 of 5~20 mg/mL. (−)-Voacangarine inhibits the cultivation of Saccharomyces cerevisiae wildtype and repair-deficient mutants[1][2].

Cat. No. Nom du produit Pureté Description Pricing
HY-N7484
(−)-Voacangarine (−)-Voacangarine is an indole alkaloid, which exhibits cytotoxic effects against cancer cells HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 of 5~20 mg/mL. (−)-Voacangarine inhibits the cultivation of Saccharomyces cerevisiae wildtype and repair-deficient mutants.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References