5459-61-0
5459-61-0
Chemical Structure
NSC-2488 hydrochloride
- CAS No.: 5459-61-0
- Formula:C15H22Cl2N2O2
- Molecular Weight:333.25
IUPAC Name: 1-(imidazo[1,2-a]pyrimidin-3-yl)-2-(5-(naphthalen-2-yl)-2H-tetrazol-2-yl)ethan-1-one
InChIKey: WDIZDHQBTFUKEG-UHFFFAOYSA-N
SMILES: OC(CC)CNCC1=C2C=C(OC)C=CC2=NC=C1.Cl.Cl
Biological Activity: NSC-2488 hydrochloride is a ROCK-II inhibitor with an IC50 of 8.02 nM. NSC-2488 hydrochloride inhibits ROCK-II enzyme activity, blocks MYPT1 phosphorylation, and induces vascular smooth muscle relaxation. NSC-2488 hydrochloride can be used for research on hypertension[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
NSC-2488 hydrochloride | NSC-2488 hydrochloride is a ROCK-II inhibitor with an IC50 of 8.02 nM. NSC-2488 hydrochloride inhibits ROCK-II enzyme activity, blocks MYPT1 phosphorylation, and induces vascular smooth muscle relaxation. NSC-2488 hydrochloride can be used for research on hypertension. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
