54767-71-4
Chemical Structure
Suloctidil hydrochloride
- CAS No.: 54767-71-4
- Formula:C20H36ClNOS
- Molecular Weight:374.02
InChIKey: JRJJHIUHSILDOH-OGPPPPIKSA-N
SMILES: [H]Cl.O[C@H]([C@H](NCCCCCCCC)C)C1=CC=C(SC(C)C)C=C1
Biological Activity: Suloctidil hydrochloride is an orally active calcium channel blocker and antifungal agent. Suloctidil hydrochloride antagonizes vasoconstriction induced by norepinephrine, angiotensin and serotonin. Suloctidil hydrochloride inhibits platelet function and exhibits neuroprotective effects. Suloctidil hydrochloride exerts inhibitory effects on Candida albicans biofilm and virulence. Suloctidil hydrochloride can be used in research on vasospasm relief, antithrombosis and superficial candidiasis[1][2][3].
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Suloctidil hydrochloride | Suloctidil hydrochloride is an orally active calcium channel blocker and antifungal agent. Suloctidil hydrochloride antagonizes vasoconstriction induced by norepinephrine, angiotensin and serotonin. Suloctidil hydrochloride inhibits platelet function and exhibits neuroprotective effects. Suloctidil hydrochloride exerts inhibitory effects on Candida albicans biofilm and virulence. Suloctidil hydrochloride can be used in research on vasospasm relief, antithrombosis and superficial candidiasis. | |||||||||||||||||||||
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[1]. Zeng B, et al. In vitro and in vivo effects of suloctidil on growth and biofilm formation of the opportunistic fungus Candida albicans. Oncotarget. 2017 Jul 25;8(41):69972-69982.
[Content Brief] - [2]. Nishi H, et al. [Effect of suloctidil in the protection of the cerebral function]. Nihon Yakurigaku Zasshi. 1983 Jul;82(1):37-46. Japanese. [Content Brief]
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[3]. Roba J, et al. Antithrombotic activity of suloctidil. Thromb Res Suppl. 1983;4:53-8.
[Content Brief]
Keywords
