54805-58-2
54805-58-2
Chemical Structure
AB182
- CAS No.: 54805-58-2
- Formula:C11H22N3O4P
- Molecular Weight:291.28
IUPAC Name: ethyl ((bis(2,2-dimethylaziridin-1-yl)phosphoryl)oxy)carbamate
InChIKey: AFKSFHAZSHQZMC-UHFFFAOYSA-N
SMILES: O=C(NOP(N1C(C)(C1)C)(N2C(C)(C2)C)=O)OCC
Biological Activity: AB-182 is an aziridine derivative and antitumor agent.AB-182 shows synergistic antitumor effects in conjunction with x-irradiation. Intermediate hydrolysis products of AB-182 may block the repair of x-irradiation-induced breaks in the DNA strands by phosphorylating their free 3'-OH end groups.
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AB182 | AB-182 is an aziridine derivative and antitumor agent.AB-182 shows synergistic antitumor effects in conjunction with x-irradiation. Intermediate hydrolysis products of AB-182 may block the repair of x-irradiation-induced breaks in the DNA strands by phosphorylating their free 3'-OH end groups. | |||||||||||||||||||||
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