56121-42-7
56121-42-7
Chemical Structure
Aurantiamide acetate
Synonym(s): Asperglaucide
- CAS. Nr.: 56121-42-7
- Formula:C27H28N2O4
- Molecular Weight:444.52
IUPAC Name: (S)-2-((S)-2-benzamido-3-phenylpropanamido)-3-phenylpropyl acetate
InChIKey: VZPAURMDJZOGHU-DQEYMECFSA-N
SMILES: O=C(N[C@H](COC(C)=O)CC1=CC=CC=C1)[C@@H](NC(C2=CC=CC=C2)=O)CC3=CC=CC=C3
Biological Activity: Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Aurantiamide acetate | 99.85% | Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases. | ||||||||||||||||||||
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References
- [1]. K Isshiki, et al. Aurantiamide Acetate, a Selective Cathepsin Inhibitor, Produced by Aspergillus Penicilloides. Biosci Biotechnol Biochem. 2001 May;65(5):1195-7. [Content Brief]
- [2]. Chi-Su Yoon, et al. Anti-neuroinflammatory Effect of Aurantiamide Acetate From the Marine Fungus Aspergillus Sp. SF-5921: Inhibition of NF-κB and MAPK Pathways in Lipopolysaccharide-Induced Mouse BV2 Microglial Cells.Int Immunopharmacol. 2014 Dec;23(2):568-74. [Content Brief]
