5635-16-5
5635-16-5
Chemical Structure
3,4-Diphenyl-5H-furan-2-one
- CAS No.: 5635-16-5
- Formula:C16H12O2
- Molecular Weight:236.27
IUPAC Name: 3,4-diphenylfuran-2(5H)-one
InChIKey: CPBAHTZRJQATEJ-UHFFFAOYSA-N
SMILES: O=C1OCC(C2=CC=CC=C2)=C1C3=CC=CC=C3
Biological Activity: 3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain[1][2].
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3,4-Diphenyl-5H-furan-2-one | 3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain. | |||||||||||||||||||||
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References
- [1]. Bai Z Q, et al. New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius[J]. Fitoterapia, 2014, 95: 194-202. [Content Brief]
- [2]. Singh P, et al. 2, 3-Diphenyltetrahydrofurans (DPTF)-A new class of stereogenic diarylheterocycles as potential COX-2 inhibitors-Computational evaluation of COX-2-DPTF binding behaviour[J]. 2006.
