57-08-9
57-08-9
Chemical Structure
6-Acetamidohexanoic acid
Synonym(s): Acexamic acid; 6-Acetamidocaproic acid
- CAS. Nr.: 57-08-9
- Formula:C8H15NO3
- Molecular Weight:173.21
IUPAC Name: 6-acetamidohexanoic acid
InChIKey: WDSCBUNMANHPFH-UHFFFAOYSA-N
SMILES: O=C(O)CCCCCNC(C)=O
Biological Activity: 6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) is a metabolite of Hexamethylene bisacetamide (HMBA) (HY-124284) with anti-pulmonary fibrosis activity. 6-Acetamidohexanoic acid does not induce differentiation of human promyelocytic leukemia cells, but is taken up by such cells. 6-Acetamidohexanoic acid serves as a carboxylic acid substrate component for constructing carboxylesterase-responsive near-infrared phototheranostic probes. 6-Acetamidohexanoic acid is applicable to research related to pulmonary fibrosis, refractory hypoxemia and cervical cancer[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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6-Acetamidohexanoic acid | 98.0% | 6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) is a metabolite of Hexamethylene bisacetamide (HMBA) (HY-124284) with anti-pulmonary fibrosis activity. 6-Acetamidohexanoic acid does not induce differentiation of human promyelocytic leukemia cells, but is taken up by such cells. 6-Acetamidohexanoic acid serves as a carboxylic acid substrate component for constructing carboxylesterase-responsive near-infrared phototheranostic probes. 6-Acetamidohexanoic acid is applicable to research related to pulmonary fibrosis, refractory hypoxemia and cervical cancer. | ||||||||||||||||||||
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6-Acetamidohexanoic acid (Standard) | ≥98% | 6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) (Standard) is the analytical standard of 6-Acetamidohexanoic acid. This product is intended for research and analytical applications. 6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) is a metabolite of Hexamethylene bisacetamide (HMBA) (HY-124284) with anti-pulmonary fibrosis activity. 6-Acetamidohexanoic acid does not induce differentiation of human promyelocytic leukemia cells, but is taken up by such cells. 6-Acetamidohexanoic acid serves as a carboxylic acid substrate component for constructing carboxylesterase-responsive near-infrared phototheranostic probes. 6-Acetamidohexanoic acid is applicable to research related to pulmonary fibrosis, refractory hypoxemia and cervical cancer. | ||||||||||||||||||||
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4-Acetamidobutanoic acid | 98.0% | 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities. | ||||||||||||||||||||
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Hexanoylglycine (Standard) | ≥98% | Hexanoylglycine (Standard) is the analytical standard of Hexanoylglycine. This product is intended for research and analytical applications. Hexanoylglycine is an endogenous metabolite present in Urine that can be used for the research of Ethylmalonic Encephalopathy. | ||||||||||||||||||||
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Hexanoylglycine-13C2,15N | Hexanoylglycine-13C2,15N is the 13C- and 15N-labeled Hexanoylglycine (HY-113150). Hexanoylglycine is an endogenous metabolite present in Urine that can be used for the research of Ethylmalonic Encephalopathy. | |||||||||||||||||||||
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Nepsilon-Acetyl-L-lysine | 99.97% | Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid. | ||||||||||||||||||||
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6-Acetamido-2-oxohexanoate | 6-Acetamido-2-oxohexanoate (6-Acetamido-2-oxohexanoic acid) is a nucleoside metabolite. | |||||||||||||||||||||
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Ac-β-Ala-OH | 98.0% | Ac-β-Ala-OH is an abnormal amino acid metabolite and also serves as a mono-N-protected amino acid (MPAA) ligand. Ac-β-Ala-OH supports the β-C (sp3)-H arylation of aliphatic carboxylic acids and also serves as a starting building block for the reverse MAP core in the construction of the gonorrhea vaccine candidate TMCP2. | ||||||||||||||||||||
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N-Heptanoylglycine | 99.43% | N-Heptanoylglycine is a Glycine (HY-Y0966) derivative. | ||||||||||||||||||||
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N-Valerylglycine | N-Valerylglycine is a Glycine (HY-Y0966) derivative. | |||||||||||||||||||||
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5-Acetamidopentanoic acid | 98.86% | 5-Acetamidopentanoic acid (5-(Acetylamino)-pentanoic acid) is a fungal metabolite. | ||||||||||||||||||||
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2-Octanamidoacetic acid-13C2,15N | 2-Octanamidoacetic acid-13C2,15N (N-octanoylglycine-13C2,15N) is the 13C- and 15N-labeled 2-Octanamidoacetic acid (HY-W099646). | |||||||||||||||||||||
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References
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[1]. Daoudal P, et al. Hypoxémies dites réfractaires: traitement par acide acéxamique [So-called refractory hypoxemia: treatment with acexamic acid]. Nouv Presse Med. 1979 Dec 3;8(47):3899. French. PMID: 95046.
[Content Brief] - [2]. Li L, et al. A carboxylesterase-activatable near-infrared phototheranostic probe for tumor fluorescence imaging and photodynamic therapy. RSC Adv. 2022;12(54):35477-35483. Published 2022 Dec 12. [Content Brief]
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[3]. Harpalani AD, et al. Alkylamides as inducers of human leukemia cell differentiation: a quantitative structure-activity relationship study using comparative molecular field analysis. Cancer Res. 1993 Feb 15;53(4):766-71. PMID: 8428356.
[Content Brief]
