580-22-3
580-22-3
Chemical Structure
2-Aminoquinoline
Synonym(s): 2-Quinolinamine
- CAS No.: 580-22-3
- Formula:C9H8N2
- Molecular Weight:144.18
IUPAC Name: quinolin-2-amine
InChIKey: GCMNJUJAKQGROZ-UHFFFAOYSA-N
SMILES: NC1=NC2=CC=CC=C2C=C1
Biological Activity: 2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1][2].
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2-Aminoquinoline | 99.95% | 2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents. | ||||||||||||||||||||
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2-Aminoquinoline (Standard) | ≥98% | 2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents. | ||||||||||||||||||||
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References
- [1]. Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60(16):7146-7165. [Content Brief]
- [2]. Smee DF, et, al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52. [Content Brief]
