58045-23-1
58045-23-1
Chemical Structure
Zuclopenthixol dihydrochloride
Synonym(s): (Z)-Clopenthixol dihydrochloride
- CAS No.: 58045-23-1
- Formula:C22H27Cl3N2OS
- Molecular Weight:473.89
IUPAC Name: (Z)-2-(4-(3-(2-chloro-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethan-1-ol dihydrochloride
InChIKey: LPWNZMIBFHMYMX-MHKBYHAFSA-N
SMILES: ClC1=CC2=C(C=C1)SC3=C(C=CC=C3)/C2=C/CCN4CCN(CC4)CCO.[H]Cl.[H]Cl
Biological Activity: Zuclopenthixol ((Z)-Clopenthixol) dihydrochloride is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist. Zuclopenthixol dihydrochloride is used in the study of schizophrenia[1][2][3].
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Zuclopenthixol dihydrochloride | Zuclopenthixol ((Z)-Clopenthixol) dihydrochloride is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist. Zuclopenthixol dihydrochloride is used in the study of schizophrenia. | |||||||||||||||||||||
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Zuclopenthixol dihydrochloride (Standard) | ≥98% | Zuclopenthixol (dihydrochloride) (Standard) is the analytical standard of Zuclopenthixol (dihydrochloride). This product is intended for research and analytical applications. Zuclopenthixol ((Z)-Clopenthixol) dihydrochloride is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist. Zuclopenthixol dihydrochloride is used in the study of schizophrenia. | ||||||||||||||||||||
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References
- [1]. Khalifa AE, et al. Pro-oxidant activity of zuclopenthixol in vivo: differential effect of the drug on brain oxidative status of scopolamine-treated rats. Hum Exp Toxicol. 2004 Aug;23(9):439-45. [Content Brief]
- [2]. Manzaneque JM, et al. An ethopharmacological assessment of the effects of zuclopenthixol on agonistic interactions in male mice. Methods Find Exp Clin Pharmacol. 1999 Jan-Feb;21(1):11-5. [Content Brief]
- [3]. Bryan EJ, et al. Zuclopenthixol dihydrochloride for schizophrenia. Cochrane Database Syst Rev. 2017 Nov 16;11(11):CD005474. [Content Brief]
