58479-71-3
58479-71-3
Chemical Structure
5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine
- CAS No.: 58479-71-3
- Formula:C13H18N2O6S
- Molecular Weight:330.36
IUPAC Name: 5-(hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: BETDENPMPLSMTA-TURQNECASA-N
SMILES: O=C(C(CO)=C1)NC(N1[C@@H]2O[C@H](CO)[C@@H]3[C@H]2OC(C)(C)O3)=S
Biological Activity: 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine | 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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