58888-84-9
58888-84-9
Chemical Structure
3-Hydroxyvalproic acid
Synonym(s): 3-Hydroxy VPA
- CAS No.: 58888-84-9
- Formula:C8H16O3
- Molecular Weight:160.21
IUPAC Name: 3-hydroxy-2-propylpentanoic acid
InChIKey: LLPFTSMZBSRZDV-UHFFFAOYSA-N
SMILES: CCC(O)C(CCC)C(O)=O
Biological Activity: 3-Hydroxyvalproic acid (3-Hydroxy VPA) is a metabolite of valproic acid. 3-Hydroxyvalproic acid is a weak inhibitor of enzymes related to the mitochondrial β-oxidation pathway. 3-Hydroxyvalproic acid is promising for research of diseases related to abnormal valproic acid metabolism[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Hydroxyvalproic acid | 99.90% | 3-Hydroxyvalproic acid (3-Hydroxy VPA) is a metabolite of valproic acid. 3-Hydroxyvalproic acid is a weak inhibitor of enzymes related to the mitochondrial β-oxidation pathway. 3-Hydroxyvalproic acid is promising for research of diseases related to abnormal valproic acid metabolism. | ||||||||||||||||||||
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References
- [1]. Heinemeyer G, et al. Oxidation and glucuronidation of valproic acid in male rats--influence of phenobarbital, 3-methylcholanthrene, beta-naphthoflavone and clofibrate. Biochem Pharmacol. 1985 Jan 1;34(1):133-9. [Content Brief]
- [2]. Prickett KS, et al. Metabolism of valproic acid by hepatic microsomal cytochrome P-450. Biochem Biophys Res Commun. 1984 Aug 16;122(3):1166-73.
- [3]. Bello-Ramírez AM, et al. Do structural properties explain the anticonvulsant activity of valproate metabolites? A QSAR analysis. Epilepsia. 2002 May;43(5):475-81. [Content Brief]
