59593-16-7
Chemical Structure
Neothramycin A
- CAS No.: 59593-16-7
- Formula:C13H14N2O4
- Molecular Weight:262.26
IUPAC Name: (3S,11aS)-3,8-dihydroxy-7-methoxy-1,2,3,11a-tetrahydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one
InChIKey: FXMOIYLVKOALHC-MADCSZMMSA-N
SMILES: O=C1C2=CC(OC)=C(O)C=C2N=C[C@@]3([H])N1[C@H](CC3)O
Biological Activity: Neothramycin A is an antibiotic, which can be isolated from Streptomyces. Neothramycin A exhibits board spectrum antimicrobial activity, inhibits Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli W677, and Saccharomyces cerevisia with MIC of 25-50 μg/mL. Neothramycin A exhibits antitumor efficacy against leukemia in mouse models[1].
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Neothramycin A | Neothramycin A is an antibiotic, which can be isolated from Streptomyces. Neothramycin A exhibits board spectrum antimicrobial activity, inhibits Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli W677, and Saccharomyces cerevisia with MIC of 25-50 μg/mL. Neothramycin A exhibits antitumor efficacy against leukemia in mouse models. | |||||||||||||||||||||
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