60325-46-4
Chemical Structure
Sulprostone
Synonym(s): SHB 286; CP-34089; ZK-57671
- CAS No.: 60325-46-4
- Formula:C23H31NO7S
- Molecular Weight:465.56
IUPAC Name: (Z)-7-((1R,2R,3R)-3-hydroxy-2-((R,E)-3-hydroxy-4-phenoxybut-1-en-1-yl)-5-oxocyclopentyl)-N-(methylsulfonyl)hept-5-enamide
InChIKey: UQZVCDCIMBLVNR-TWYODKAFSA-N
SMILES: O=C(NS(=O)(C)=O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC=C2)[C@H](O)CC1=O
Biological Activity:
Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery[1][2][3].
The product specifications provided below refer solely to the active content of Sulprostone.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sulprostone | 95.01% | Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery. The product specifications provided below refer solely to the active content of Sulprostone. |
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Similarity Score 0.83
HY-13715816-Phenoxy tetranor Prostaglandin E2 -
Similarity Score 0.73
HY-106550Enprostil -
Similarity Score 0.71
HY-1242099-keto Fluprostenol -
Similarity Score 0.71
HY-13886817-Phenyl trinor prostaglandin E2 ethyl amide -
Similarity Score 0.70
HY-12417516-Phenoxy prostaglandin F2α ethyl amide -
Similarity Score 0.69
HY-12803917-Phenyl-ω-trinor-PGE2 -
Similarity Score 0.69
HY-1370439-Keto Travoprost -
Similarity Score 0.68
HY-13906316-Phenoxy tetranor prostaglandin F2α -
Similarity Score 0.68
HY-1688029-Keto tafluprost -
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References
- [1]. S Narumiya, et al. Prostanoid receptors: structures, properties, and functions. Physiol Rev. 1999 Oct;79(4):1193-226. [Content Brief]
- [2]. Jenny Bulgarelli, et al. Skewing effect of sulprostone on dendritic cell maturation compared with dinoprostone. Cytotherapy. 2018 Jun;20(6):851-860. [Content Brief]
- [3]. Yifan Shi, et al. Bioanalysis of sulprostone, a prostaglandin E 2 analogue and selective EP 3 agonist, in monkey plasma by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:51-57. [Content Brief]
